GenomeRNAi - a database for RNAi phenotypes and reagents

What is GenomeRNAi?

GenomeRNAi is a database containing phenotypes from RNA interference (RNAi) screens in Drosophila and Homo sapiens. In addition, the database provides an updated resource of RNAi reagents and their predicted quality.

RNAi screening data is extracted from the literature by manual curation, but we also provide a functionality for direct submission by data producers - our preferred option!

Please remember to cite GenomeRNAi to help us secure future funding. We also appreciate your feedback and suggestions!


the GenomeRNAi database either by viewing all screens, by looking at frequent hitters or by choosing an example below

Genes: 841 , CTNNB1 , Pvr , CG9171 , FBgn0036141
Reagents: DRSC03504 , BKN25930
Phenotypes: regulation , decreased , Toll


  • GenomeRNAi v15 released11 January, 2016
    Thanks to the import of the Broad Institute's Achilles Project , the number of gene-phenotype associations has more than doubled to over 2,5 million entries. The database now provides data from 452 human RNAi screens and 201 screens in D.melanogaster.
    NEW: Try out our full page view with a download option to obtain all phenotypes for a given gene or reagent! We have also added a new search option – search for screens via PubMed ID or first author.
    As ever, we welcome your own data submission!

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Please cite: Schmidt et al. (2012). GenomeRNAi: a database for cell-based and in vivo RNAi phenotypes, 2013 update.